CHEMBL4640703


SMILES O=C(Nc1ccc(F)cc1-c1cccc(Cl)c1)OCC1CCNCC1
InChIKey HLWLKLSVJQAUNS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 362.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.08 10.08 10.08 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.24 8.24 8.24 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.47 9.47 9.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pEC50 7.58 7.86 8.16 ChEMBL