CHEMBL4447330


SMILES COc1ccc(N2CCN(CCCCCCN3C(=O)c4cccc5cccc(c45)C3=O)CC2)cc1
InChIKey UGOXZHALYQBPNO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 471.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.24 5.24 5.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.22 4.22 4.22 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.45 5.45 5.45 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.4 4.4 4.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database