CHEMBL4650736


SMILES C[N+]12CCC(CC1)[C@@H](OC(=O)Nc1ccc(F)cc1-c1cccc(Cl)c1)C2
InChIKey PRPBOUUIRMITJF-WDHIMTGQSA-O

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 389.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.14 10.14 10.14 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.48 8.48 8.48 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.96 9.96 9.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pEC50 8.2 8.43 8.66 ChEMBL