CHEMBL464191


SMILES O=C1N(CCCN2CCCC2)CN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2
InChIKey ZQXJEKRACRYDRN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 576.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.49 8.49 8.49 ChEMBL
δ OPRD Human Opioid A pKi 5.62 5.62 5.62 ChEMBL
κ OPRK Human Opioid A pKi 7.19 7.19 7.19 ChEMBL
μ OPRM Human Opioid A pKi 6.36 6.36 6.36 ChEMBL
δ OPRD Human Opioid A pKi 5.62 5.62 5.62 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.49 8.49 8.49 PDSP Ki database
κ OPRK Human Opioid A pKi 7.19 7.19 7.19 PDSP Ki database
μ OPRM Human Opioid A pKi 6.36 6.36 6.36 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database