CHEMBL4455570


SMILES CN1CC=C(c2nsnc2OCCCN2CCN(CCCCC3CCN(CC(=O)N4c5ccccc5NC(=O)c5ccccc54)CC3)CC2)CC1
InChIKey XFGSFWFIJFNGQY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 1
Rotatable bonds 13
Molecular weight (Da) 712.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.47 7.47 7.47 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.59 8.59 8.59 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.88 7.88 7.88 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 10.1 10.1 10.1 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.84 8.84 8.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database