CHEMBL4644906


SMILES O=C1CCc2cc(OCCCCCCN3CCN(c4nsc5ccccc45)CC3)ccc2N1
InChIKey JNMNZCISRVSLEC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.09 6.09 6.09 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.41 7.41 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database