CHEMBL473904


SMILES O=C1N(CCN2CCCC2)CN(c2ccccc2)C12CCN(Cc1c(Cl)cccc1Cl)CC2
InChIKey PAUCBEYUHQSRSV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.64 8.64 8.64 ChEMBL
δ OPRD Human Opioid A pKi 6.27 6.27 6.27 ChEMBL
κ OPRK Human Opioid A pKi 7.82 7.82 7.82 ChEMBL
NOP OPRX Human Opioid A pKi 8.64 8.64 8.64 PDSP Ki database
δ OPRD Human Opioid A pKi 6.27 6.27 6.27 PDSP Ki database
κ OPRK Human Opioid A pKi 7.82 7.82 7.82 PDSP Ki database
μ OPRM Human Opioid A pKi 7.43 7.43 7.43 PDSP Ki database
μ OPRM Human Opioid A pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database