CHEMBL470432


SMILES CCCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1
InChIKey FZGWDCDUMFWUEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Rat 5-Hydroxytryptamine A pIC50 5.34 5.34 5.34 ChEMBL
α1B ADA1B Human Adrenoceptors A pIC50 6.84 6.84 6.84 ChEMBL
α1D ADA1D Human Adrenoceptors A pIC50 6.69 6.69 6.69 ChEMBL
α2B ADA2B Human Adrenoceptors A pIC50 6.02 6.02 6.02 ChEMBL
α2C ADA2C Human Adrenoceptors A pIC50 6.13 6.13 6.13 ChEMBL
α1A ADA1A Human Adrenoceptors A pIC50 7.13 7.13 7.13 ChEMBL
α2A ADA2A Human Adrenoceptors A pIC50 6.05 6.05 6.05 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 6.55 6.55 6.55 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.14 7.14 7.14 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.3 5.3 5.3 ChEMBL