CHEMBL472086


SMILES CCCCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4cc(Cl)c(Cl)cc43)CC2)C1=O
InChIKey MEFGLNPAZYTMOF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 556.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.91 7.91 7.91 ChEMBL
δ OPRD Human Opioid A pKi 5.3 5.3 5.3 ChEMBL
κ OPRK Human Opioid A pKi 6.8 6.8 6.8 ChEMBL
μ OPRM Human Opioid A pKi 6.51 6.51 6.51 ChEMBL
NOP OPRX Human Opioid A pKi 7.91 7.91 7.91 PDSP Ki database
δ OPRD Human Opioid A pKi 5.3 5.3 5.3 PDSP Ki database
κ OPRK Human Opioid A pKi 6.8 6.8 6.8 PDSP Ki database
μ OPRM Human Opioid A pKi 6.51 6.51 6.51 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database