CHEMBL1259203


SMILES CN1CCC(c2cn(-c3ccc(F)cc3)c3ccc(-c4cncnc4)cc23)CC1
InChIKey WAWSGWZTHJAPIA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 8.72 8.72 8.72 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.28 9.28 9.28 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.58 6.75 6.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database