CHEMBL472677


SMILES O=C1N(CC2CC2)CN(c2ccccc2)C12CCN(C(c1ccccc1)c1ccccc1)CC2
InChIKey DFUWOFTVSMOGGO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 451.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.08 7.08 7.08 ChEMBL
δ OPRD Human Opioid A pKi 5.27 5.27 5.27 ChEMBL
κ OPRK Human Opioid A pKi 6.2 6.2 6.2 ChEMBL
μ OPRM Human Opioid A pKi 5.28 5.28 5.28 ChEMBL
δ OPRD Human Opioid A pKi 5.27 5.27 5.27 PDSP Ki database
μ OPRM Human Opioid A pKi 5.28 5.28 5.28 PDSP Ki database
κ OPRK Human Opioid A pKi 6.2 6.2 6.2 PDSP Ki database
NOP OPRX Human Opioid A pKi 7.08 7.08 7.08 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database