CHEMBL473278


SMILES CC1(C)CCC(N2CCC3(CC2)C(=O)N(CCNCC2CC2)CN3c2ccccc2)c2ccccc21
InChIKey LQMOLTNLIVUBMU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 486.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 6.76 6.76 6.76 ChEMBL
μ OPRM Human Opioid A pKi 6.62 6.62 6.62 ChEMBL
NOP OPRX Human Opioid A pKi 9.1 9.1 9.1 PDSP Ki database
δ OPRD Human Opioid A pKi 5.54 5.54 5.54 PDSP Ki database
μ OPRM Human Opioid A pKi 6.62 6.62 6.62 PDSP Ki database
δ OPRD Human Opioid A pKi 5.54 5.54 5.54 ChEMBL
κ OPRK Human Opioid A pKi 6.76 6.76 6.76 PDSP Ki database
NOP OPRX Human Opioid A pKi 9.1 9.1 9.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database