CHEMBL473700


SMILES CCCCNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O
InChIKey ZBVIRJRRQRKZEM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 488.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.4 9.4 9.4 ChEMBL
δ OPRD Human Opioid A pKi 6.06 6.06 6.06 ChEMBL
κ OPRK Human Opioid A pKi 8.0 8.0 8.0 ChEMBL
μ OPRM Human Opioid A pKi 7.44 7.44 7.44 ChEMBL
NOP OPRX Human Opioid A pKi 9.4 9.4 9.4 PDSP Ki database
δ OPRD Human Opioid A pKi 6.06 6.06 6.06 PDSP Ki database
κ OPRK Human Opioid A pKi 8.0 8.0 8.0 PDSP Ki database
μ OPRM Human Opioid A pKi 7.44 7.44 7.44 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database