CHEMBL450341


SMILES CCCN1C(=O)N2C[C@@H](CC)N=C2c2[nH]c(C34CCC(O)(CC3)CC4)nc21
InChIKey UOQYIXROQIKTLQ-JYMLRBTQSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 371.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 5.57 5.57 5.57 ChEMBL
A1 AA1R Rat Adenosine A pKd 8.88 8.88 8.88 ChEMBL
A1 AA1R Rat Adenosine A pKi 8.22 8.22 8.22 ChEMBL
A2B AA2BR Human Adenosine A pKi 6.24 6.24 6.24 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.36 5.36 5.36 ChEMBL
A1 AA1R Human Adenosine A pKi 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database