CHEMBL475094


SMILES C=CCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey NJGHPWBZRUJKIQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 472.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.05 9.05 9.05 ChEMBL
δ OPRD Human Opioid A pKi 5.6 5.6 5.6 ChEMBL
κ OPRK Human Opioid A pKi 6.68 6.68 6.68 ChEMBL
μ OPRM Human Opioid A pKi 6.7 6.7 6.7 ChEMBL
δ OPRD Human Opioid A pKi 5.6 5.6 5.6 PDSP Ki database
NOP OPRX Human Opioid A pKi 9.05 9.05 9.05 PDSP Ki database
μ OPRM Human Opioid A pKi 6.7 6.7 6.7 PDSP Ki database
κ OPRK Human Opioid A pKi 6.68 6.68 6.68 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database