CHEMBL475707


SMILES CC(C)NCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O
InChIKey YNNJYRPLVQZFTC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 ChEMBL
δ OPRD Human Opioid A pKi 5.97 5.97 5.97 ChEMBL
κ OPRK Human Opioid A pKi 7.4 7.4 7.4 ChEMBL
μ OPRM Human Opioid A pKi 6.87 6.87 6.87 ChEMBL
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 PDSP Ki database
δ OPRD Human Opioid A pKi 5.97 5.97 5.97 PDSP Ki database
κ OPRK Human Opioid A pKi 7.4 7.4 7.4 PDSP Ki database
μ OPRM Human Opioid A pKi 6.87 6.87 6.87 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database