CHEMBL4538667


SMILES COc1ccccc1N1CCN(CCCCCCn2c(=O)n3c4c(cccc42)CCC3)CC1
InChIKey HKOFHLGKVUBWFI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 448.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.49 5.49 5.49 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.7 8.7 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database