CHEMBL475497


SMILES CC(C)CCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)C1=O
InChIKey XCHMPVBATAQYON-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 535.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.25 7.25 7.25 ChEMBL
δ OPRD Human Opioid A pKi 4.21 4.21 4.21 ChEMBL
κ OPRK Human Opioid A pKi 4.33 4.33 4.33 ChEMBL
μ OPRM Human Opioid A pKi 4.89 4.89 4.89 ChEMBL
NOP OPRX Human Opioid A pKi 7.25 7.25 7.25 PDSP Ki database
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
μ OPRM Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
κ OPRK Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database