CHEMBL4778264


SMILES O=C(O)C[C@@H](c1ccc(OCc2ccc3nc(-c4ccccc4)nn3c2)cc1)c1ccon1
InChIKey KIZDOKWMTBVGAP-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 440.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Human Free fatty acid A pKi 7.1 7.1 7.1 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pKd 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Mouse Free fatty acid A pEC50 5.42 5.42 5.42 ChEMBL
FFA1 FFAR1 Rat Free fatty acid A pEC50 4.85 4.85 4.85 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pEC50 6.22 7.08 7.85 ChEMBL