CHEMBL457026
SMILES | CC(C)OC(=O)N1CC=C(c2cn(-c3cccnc3F)nn2)CC1 |
InChIKey | MWBWDQVGXJWEDX-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 6 |
Hydrogen bond donors | 0 |
Rotatable bonds | 3 |
Molecular weight (Da) | 331.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
mGlu1 | GRM1 | Mouse | Metabotropic glutamate | C | pIC50 | 6.75 | 6.75 | 6.75 | ChEMBL |
mGlu1 | GRM1 | Human | Metabotropic glutamate | C | pIC50 | 7.41 | 7.41 | 7.41 | ChEMBL |
mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pIC50 | 5.41 | 5.41 | 5.41 | ChEMBL |