CHEMBL4574056


SMILES CC(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O)C(C)C
InChIKey FTKVMQSYQHWAOE-YAOOYPAMSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 7
Rotatable bonds 14
Molecular weight (Da) 746.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Mouse Melanocortin A pKd 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 8.47 8.47 8.47 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 9.7 9.7 9.7 ChEMBL
MC3 MC3R Mouse Melanocortin A pEC50 8.22 8.22 8.22 ChEMBL
MC4 MC4R Mouse Melanocortin A pEC50 6.8 6.8 6.8 ChEMBL