CHEMBL4594753


SMILES CC(C)(C)CNc1nccc(NCCCN)n1
InChIKey PLQWTZPLYTZFCJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 237.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.44 7.44 7.44 ChEMBL
H3 HRH3 Human Histamine A pKi 5.25 5.25 5.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 5.97 6.63 7.29 ChEMBL
H4 HRH4 Rat Histamine A pEC50 6.72 7.18 7.64 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.4 7.46 7.53 ChEMBL