CHEMBL4802409


SMILES Cc1cc(/C=C/c2cc3c4c(c2)CCCN4CCC3)cc(C)[n+]1CCNC(=O)CCc1cn(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)cn1
InChIKey CXAKWVHJKJFJLW-UHFFFAOYSA-O

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 15
Molecular weight (Da) 859.5

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.39 7.39 7.39 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.58 8.58 8.58 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.16 7.16 7.16 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.42 8.56 8.7 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.15 8.51 8.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database