CHEMBL4595236


SMILES O=C1c2cccc3cccc(c23)N1CCCCCCN1CCN(c2ccc(C(F)(F)F)cc2)CC1
InChIKey PPFOWMXZBSOTKT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 481.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.31 4.31 4.31 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.69 5.69 5.69 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.36 5.36 5.36 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database