CHEMBL4595970


SMILES CCCN(CCCCNC(=O)c1ccc2ccccc2c1)CC1CC1c1ccc(C(F)(F)F)cc1
InChIKey YKCROHAUAFLVCV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 482.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.24 5.24 5.24 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.67 6.67 6.67 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.77 5.77 5.77 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database