CHEMBL4803797


SMILES O=C(CCCN1CCN(c2cccnc2)CC1)c1ccc(F)cc1
InChIKey LUNVFEQWDLSWQQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 327.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.83 6.85 6.87 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.52 7.53 7.53 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.01 7.01 7.01 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.52 6.52 6.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.93 5.93 5.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database