CHEMBL4596491


SMILES CC(C)(C)CNc1nccc(N2CCCNCC2)n1
InChIKey AZHUBGIQDYLZDQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 263.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.88 7.88 7.88 ChEMBL
H3 HRH3 Human Histamine A pKi 6.27 6.27 6.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 6.45 6.87 7.29 ChEMBL
H4 HRH4 Rat Histamine A pEC50 6.19 6.61 7.03 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.37 7.55 7.74 ChEMBL