CHEMBL4596571


SMILES CCCN(CCCCNC(=O)c1cc2ccccc2[nH]1)CC1CC1c1ccc(F)cc1
InChIKey HKDMXVFAYYQTRF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 421.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 4.98 4.98 4.98 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.79 5.79 5.79 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.84 5.84 5.84 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.66 6.66 6.66 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.34 7.34 7.34 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.23 5.23 5.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database