CHEMBL4596881


SMILES CC(C)(C)CNc1nccc(N2CC[C@@H](N)C2)n1
InChIKey XOGNVWVGXPSTMU-SNVBAGLBSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 249.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 8.07 8.07 8.07 ChEMBL
H3 HRH3 Human Histamine A pKi 7.86 7.86 7.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 6.87 7.62 8.38 ChEMBL
H4 HRH4 Rat Histamine A pEC50 7.47 8.11 8.75 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.84 8.14 8.45 ChEMBL