CHEMBL4598198


SMILES CC(C)(C)CNc1nccc(N2CC[C@@H](NC(=N)N)C2)n1
InChIKey RWLPUWLTJPDDAF-SNVBAGLBSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 291.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.16 7.16 7.16 ChEMBL
H3 HRH3 Human Histamine A pKi 5.95 5.95 5.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 6.64 7.43 8.21 ChEMBL
H4 HRH4 Rat Histamine A pEC50 6.84 7.85 8.86 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.05 7.25 7.45 ChEMBL