CHEMBL4803797
SMILES | O=C(CCCN1CCN(c2cccnc2)CC1)c1ccc(F)cc1 |
InChIKey | LUNVFEQWDLSWQQ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 6 |
Molecular weight (Da) | 327.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 6.83 | 6.85 | 6.87 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.52 | 7.53 | 7.53 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.85 | 6.85 | 6.85 | ChEMBL |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 6.52 | 6.52 | 6.52 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 7.01 | 7.01 | 7.01 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.93 | 5.93 | 5.93 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |