METHYSERGIDE


SMILES CCC(CO)NC(=O)[C@@H]1C=C2c3cccc4c3c(cn4C)C[C@H]2N(C)C1
InChIKey KPJZHOPZRAFDTN-NQUBZZJWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.9 7.9 7.9 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.1 7.5 7.9 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
RXFP1 RXFP1 Human Relaxin family peptide A Potency 4.4 4.4 4.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 5.97 5.97 5.97 ChEMBL