CHEMBL4857597
SMILES | O=C1CCc2cc(CCCCN3CCN(c4ccccn4)CC3)ccc2N1 |
InChIKey | NWOBFMIIGQBMFP-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 1 |
Rotatable bonds | 6 |
Molecular weight (Da) | 364.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 7.61 | 7.62 | 7.64 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 6.83 | 6.85 | 6.87 | ChEMBL |
5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 5.95 | 5.95 | 5.95 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.69 | 6.69 | 6.69 | ChEMBL |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 6.25 | 6.26 | 6.27 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 8.35 | 8.37 | 8.39 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.28 | 6.29 | 6.3 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |