CHEMBL470432


SMILES CCCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1
InChIKey FZGWDCDUMFWUEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 8.22 8.49 8.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Rat 5-Hydroxytryptamine A pIC50 5.34 5.34 5.34 ChEMBL
α1B ADA1B Human Adrenoceptors A pIC50 6.84 6.84 6.84 ChEMBL
α1D ADA1D Human Adrenoceptors A pIC50 6.69 6.69 6.69 ChEMBL
α2B ADA2B Human Adrenoceptors A pIC50 6.02 6.02 6.02 ChEMBL
α2C ADA2C Human Adrenoceptors A pIC50 6.13 6.13 6.13 ChEMBL
α1A ADA1A Human Adrenoceptors A pIC50 7.13 7.13 7.13 ChEMBL
α2A ADA2A Human Adrenoceptors A pIC50 6.05 6.05 6.05 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 6.55 6.55 6.55 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.14 7.14 7.14 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.3 5.3 5.3 ChEMBL