CHEMBL1182145


SMILES COc1cc(-c2ccccc2)ccc1OCCNC[C@H]1COc2ccccc2O1
InChIKey NTTBWNFZOZWLDB-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 6.97 6.97 6.97 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 6.88 6.88 6.88 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.73 6.73 6.73 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 6.12 6.12 6.12 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.67 6.67 6.67 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.06 7.06 7.06 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database