CHEMBL491466


SMILES CCCN(CCCCn1cc(-c2ccc(-c3ccccc3)cc2)nn1)C1CC=C(C#Cc2ccccc2)CC1
InChIKey VZFYQAAXSLVYIL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.77 5.77 5.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 6.71 6.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 6.71 6.74 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.82 6.82 6.82 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 5.96 5.96 5.96 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database