CHEMBL4747225


SMILES O=S(=O)(N[C@@H]1CCN(CCCc2noc3ccccc23)C1)c1ccc2ccccc2c1
InChIKey QGVGRVIBOJVENZ-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.61 9.61 9.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.7 9.7 9.7 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database