CHEMBL4748337


SMILES Cn1ccc2c(NC(=O)CCN3CCCc4ccccc43)cccc21
InChIKey XBTJKTGWGACFOJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 333.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 4.92 4.92 4.92 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.64 5.64 5.64 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 6.37 6.37 6.37 ChEMBL