CHEMBL4749384


SMILES O=C(c1cccc(F)c1-c1ncccn1)N1[C@H]2CC[C@@H]1C[C@H]2Nc1ncc(C(F)(F)F)cc1Cl
InChIKey KLQOGXRJHFIGAB-XWIAVFTESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 491.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.85 7.85 7.85 ChEMBL
OX2 OX2R Human Orexin A pKi 6.27 6.27 6.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database