CHEMBL4750440


SMILES O=C(c1ccccc1-c1ncccn1)N1[C@H]2CC[C@@H]1C[C@H]2Nc1cnc(C(F)(F)F)cn1
InChIKey INBVGVYJGNXKID-XYPHTWIQSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 440.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.72 7.72 7.72 ChEMBL
OX2 OX2R Human Orexin A pKi 6.28 6.28 6.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database