CHEMBL494947


SMILES Clc1cccc(COc2cncc(N3CCNCC3)n2)c1
InChIKey PCWGGOVOEWHPMG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 304.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.03 8.35 9.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.09 7.09 7.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.18 7.18 7.18 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.09 8.72 9.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.85 6.99 7.12 ChEMBL