CHEMBL497746


SMILES CC(C)[C@H](NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(C(=O)[C@H](C)Cc2ccc(Cl)cc2)CC1
InChIKey ROSDSGGMKIYLIM-ZBLYBZFDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 530.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Rat Melanocortin A pKi 6.47 6.47 6.47 ChEMBL
MC3 MC3R Mouse Melanocortin A pKi 6.72 6.72 6.72 ChEMBL
MC4 MC4R Mouse Melanocortin A pKi 8.46 8.46 8.46 ChEMBL
MC5 MC5R Human Melanocortin A pKi 5.96 5.96 5.96 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.31 6.31 6.31 ChEMBL
ghrelin GHSR Human Ghrelin A pKi 6.62 6.62 6.62 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.12 8.12 8.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 6.57 6.57 6.57 ChEMBL