CHEMBL499169


SMILES CC(C)N(CCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)C1=O)C(C)C
InChIKey DWDYTNBJCKOHTA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 592.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 5.32 5.32 5.32 ChEMBL
μ OPRM Human Opioid A pKi 5.72 5.72 5.72 ChEMBL
NOP OPRX Human Opioid A pKi 7.92 7.92 7.92 PDSP Ki database
δ OPRD Human Opioid A pKi 5.32 5.32 5.32 PDSP Ki database
κ OPRK Human Opioid A pKi 6.17 6.17 6.17 PDSP Ki database
μ OPRM Human Opioid A pKi 5.72 5.72 5.72 PDSP Ki database
κ OPRK Human Opioid A pKi 6.17 6.17 6.17 ChEMBL
NOP OPRX Human Opioid A pKi 7.92 7.92 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database