CHEMBL476394


SMILES O=C1c2ccccc2CCCN1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1
InChIKey UIFDNPUSYCXLPI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 445.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 5.76 5.76 5.76 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.84 7.84 7.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.98 7.99 8.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.44 7.44 7.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database