CHEMBL499324


SMILES CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4C#N)no3)ccc21
InChIKey NVSKXWGRIBCWNF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 8.16 8.16 8.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Rat Cannabinoid A pEC50 9.89 9.89 9.89 ChEMBL
CB2 CNR2 Human Cannabinoid A pEC50 9.07 9.28 9.48 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 6.15 6.15 6.15 ChEMBL