CHEMBL4764827


SMILES CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O
InChIKey MKWJFYTWCUVRPG-UYEZAFAQSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 6
Rotatable bonds 15
Molecular weight (Da) 706.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Mouse Melanocortin A pKd 5.4 5.4 5.4 ChEMBL
MC4 MC4R Mouse Melanocortin A pKi 5.4 5.4 5.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 7.41 7.41 7.41 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 6.91 6.91 6.91 ChEMBL
MC3 MC3R Mouse Melanocortin A pEC50 6.96 6.96 6.96 ChEMBL