CHEMBL477200


SMILES COc1ccccc1N1CCN(CCCSc2nc3ccccc3s2)CC1
InChIKey XGBAGSLZEBECDF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 399.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.89 5.89 5.89 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.59 7.59 7.59 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.77 9.15 9.54 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.77 9.15 9.54 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.89 5.89 5.89 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database