CHEMBL477250


SMILES COc1ccccc1N1CCN(CCCCN2CCc3ccccc3C2=O)CC1
InChIKey UIFXLMHCLOJOQC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 393.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.6 5.6 5.6 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.72 8.72 8.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.58 8.65 8.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.68 7.91 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 8.48 8.48 8.48 ChEMBL