CHEMBL4776204


SMILES N=C(N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C(N)=O)c1ccccc1
InChIKey VREKBHVPVINEDT-ISKFKSNPSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 6
Rotatable bonds 12
Molecular weight (Da) 500.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF2 NPFF2 Mouse Neuropeptide FF/neuropeptide AF A pKi 6.08 6.08 6.08 ChEMBL
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pKi 7.24 7.24 7.24 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pKi 6.59 6.59 6.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pIC50 7.68 7.68 7.68 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pIC50 6.41 6.41 6.41 ChEMBL