CHEMBL477765


SMILES COc1ccccc1N1CCN(CCCCSc2nc3ccccc3s2)CC1
InChIKey ISSGVAQXZMSDSW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 413.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.57 9.57 9.57 ChEMBL
D1 DRD1 Rat Dopamine A pKi 5.7 5.7 5.7 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.57 9.57 9.57 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database