CHEMBL511649


SMILES CC(=O)CN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O
InChIKey SFJKZKRGYFETAG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 445.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.35 8.35 8.35 ChEMBL
δ OPRD Human Opioid A pKi 6.1 6.1 6.1 ChEMBL
κ OPRK Human Opioid A pKi 7.25 7.25 7.25 ChEMBL
μ OPRM Human Opioid A pKi 7.85 7.85 7.85 ChEMBL
δ OPRD Human Opioid A pKi 6.1 6.1 6.1 PDSP Ki database
μ OPRM Human Opioid A pKi 7.85 7.85 7.85 PDSP Ki database
κ OPRK Human Opioid A pKi 7.25 7.25 7.25 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.35 8.35 8.35 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database